Why Graduate Students Should Meditate

By: Caitlin Millett, 3rd year PhD candidate in the Neuroscience Graduate Program

“Educating the mind without educating the heart is no education at all.”
― Aristotle


Moyan Brenn (Flickr)

Meditation is an ancient practice dating back at least three millennia. It’s a fundamental component of many Eastern religious traditions and belief systems including Hinduism, Buddhism, and Daoism, to name just a few.

The term meditation refers to a broad variety of practices meant to clear the mind and build compassion and kindness. It may also ease some health issues, such as high blood pressure, depression, anxiety, and stress. The National Center for Complementary and Alternative Medicine (NCCAM), a component of the National Institutes of Health, notes that:

“Meditation may be practiced for many reasons, such as to increase calmness and physical relaxation, to improve psychological balance, to cope with illness, or to enhance overall health and well-being.”

Due to its purported benefits, recent decades have seen increased interest and additional funding for research on meditation and mindfulness. Moreover, mindfulness has reached an almost fad-like status in the Western world due to its potential positive effects on health.

In December, Penn State Hershey Medical Center offered a free seven-week class to learn meditation. Similarly, the Penn State Hershey University Fitness Center recently held their first ever meditation sessions. But for most of us, especially those of us in the sciences, the question still lingers- is there data supporting the benefits of meditation?

An enlightening seminar The Science of Meditation, held on Wednesday, August 27th by the Association of Indians at Hershey, shed light on the science behind some of the benefits of meditative practices.

Reduces stress

One of the longest-studied benefits of meditation is the relaxation response. The relaxation response is defined as a “…physical state of deep rest that changes the physical and emotional responses to stress.

Dr. Herbert Benson, Associate Professor of Medicine at Harvard Medical School and founder of the Mind Body Medical Institute, pioneered this research field with his work in transcendental meditation (TM) in the early ’70s. Dr. Benson’s meditation technique is meant to reverse and counteract the effects of the fight-or-flight response (increased production of epinephrine and norepinephrine, increased heart rate and blood pressure) and has discovered that meditation can decrease blood pressure while increasing feelings of peace and contentment.

Other, more recent work has corroborated these findings. A study by Schneider and colleagues (2009) published in the journal Circulation found that long term practice of TM can improve outcomes in a population at high risk for stroke and heart attack. In fact, Schneider found that the patients’ risk was cut in half when practicing TM, and were disease-free for longer than their counterparts (all subjects had coronary artery disease). Though it is known that hormones such as cortisol and catecholamines (epinephrine and norepinephrine) are elevated in stress, it is unknown if TM caused a reduction in these hormones, thereby leading to better outcomes.

Alters subjective perception of pain

insulaA study by Zeidan (2012) at Wake Forest School of Medicine showed that practicing mindfulness meditations (focusing your complete attention on one thing, e.g., your breath) for twenty minutes a day for four days can actually reduce perceived intensity of a painful stimulus (a hot metal plate on the calf) by 40%, and can reduce the unpleasantness of the noxious stimulus by a whopping 57%!

Using fMRI imaging, the areas of the brain which normally respond to pain – the primary and secondary somatosensory cortices – had reduced activation post-meditation. Subjects who experienced the greatest reduction in pain intensity had the largest increase in activity of the insula and cingulate cortex-two areas implicated in human empathy. Also, subjects that reported the largest reductions in unpleasantness of the hot plate had the greatest reduction in thalamus activation- which gates all incoming sensory information before it reaches the cortex. These latter subjects also showed increased activation of the orbitofrontal cortex, an area important for logical decision making.

Overall, it seems that practicing focused attention through mindfulness meditation actually reduced the subjective experience of pain.

Reduces chance of depressive relapse

One of the major criticisms of research on meditation has been the paucity of high-quality, well-funded work. Due to an increase in government funding in recent years, there have been several valuable studies published in high impact journals. One of these, published in Archives of General Psychiatry (2010), found mindfulness-based cognitive therapy (MBCT), a secular and clinically based practice, can reduce relapses into depression:

“…for depressed patients who are unwilling or unable to tolerate long term maintenance antidepressant treatment MBCT offers equivalent protection from relapse.”

Another study at Oxford University (2013) corroborated this result, finding MBCT can reduce relapse into depression by 44%. Furthermore, MBCT is now included as a group intervention in the American Psychiatric Association’s Practice Guideline for the Treatment of Patients with Major Depressive Disorder.

Compassionate thinking begets compassionate behavior

A study by Lutz and colleagues (2008) at the University of Wisconsin-Madison found that meditating on compassion can alter our brains’ functionality to become more compassionate.


Tibetan monks. Wonderlane (Flickr)

By comparing novice meditators with a group of Tibetan monks who had over 10,000 hours of practice, this study was the first to show (with fMRI) that emotions such as loving-kindness and compassion can be learned in the same way as playing a musical instrument or being adept in a sport. Lutz found that presentation of emotional cues (vocalizations of distress) was associated with increased activation in the insula and cingulate cortices during meditation. Moreover, activation of these regions was greater in expert meditators compared to novices.

Clearly there has been a great deal of intriguing work put forth to support meditation as an alternative or supplement to traditional medicine. However, this research is still in its early stages and anyone who is thinking of taking up meditation to help treat an illness should consult with their health care provider first. On the other hand, meditation is a great tool to simply reduce stress or increase happiness.

To learn more about meditation, please visit the NIH webpage. If you or anyone you know is suffering with a mental illness and would like to speak to a medical professional at Penn State College of Medicine, please visit the Psychiatry homepage.


  1. NIH on Meditation: http://nccam.nih.gov/health/meditation/overview.htm
  2. Compassion at UWM: Antoine Lutz, Julie Brefczynski-Lewis, Tom Johnstone, Richard J. Davidson. Regulation of the Neural Circuitry of Emotion by Compassion Meditation: Effects of Meditative Expertise.PLoS ONE, 2008; 3 (3): e1897 DOI:1371/journal.pone.0001897
  3. Stress reduction: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268875/pdf/nihms-34949.pdf
  4. Mayo Clinic on tai chi: http://www.mayoclinic.org/healthy-living/stress-management/in-depth/tai-chi/art-20045184
  5. Relaxation response: http://www.relaxationresponse.org/
  6. Oxford study on MBCT: Williams, J. M. G., Crane, C., Barnhofer, T., Brennan, K., Duggan, D. S., Fennell, M. J. V., Hackmann, A., Krusche, A., Muse, K., Von Rohr, I. R., Shah, D., Crane, R. S., Eames, C., Jones M., Radford, S., Silverton, S., Sun, Y., Weatherley-Jones, E., Whitaker, C. J., Russell, D., & Russell, I. T. (2013, December 2). Mindfulness-Based Cognitive Therapy for Preventing Relapse in Recurrent Depression: A Randomized Dismantling Trial. Journal of Consulting and Clinical Psychology. Advance online publication. doi: 10.1037/a0035036.
  7. Segal ZV, Bieling P, Young T, et al. Antidepressant monotherapy vs sequential pharmacotherapy and mind- fulness-based cognitive therapy, or placebo, for relapse prophylaxis in recurrent depression. Arch Gen Psychiatry 2010; 67:1256–64.
  8. Work Group On Major Depressive Disorder. American Psychiatric Association practice guideline for the treatment of patients with major depressive disorder, third edi- tion. Arlington, VA: American Psychiatric Publishing; 2010.
  9. Criticism: Krisanaprakornkit T, Ngamjarus C, Witoonchart C, Piyavhatkul N (2010). “Meditation therapies for attention-deficit/hyperactivity disorder (ADHD)”. In Krisanaprakornkit, Thawatchai.Cochrane Database Syst Rev 6 (6): CD006507.doi:1002/14651858.CD006507.pub2PMID 20556767.
  10. Zeidan, et al., Mindfulness meditation-related pain relief: Evidence for unique brain mechanisms in theregulation of pain, Neurosci. Lett. (2012), http://dx.doi.org/10.1016/j.neulet.2012.03.082
  11. Hölzel, Britta K. et al. Mindfulness practice leads to increases in regional brain gray matter density. Psychiatry Research: Neuroimaging , Volume 191 , Issue 1 , 36 – 43.

2 thoughts on “Why Graduate Students Should Meditate

  1. A few related links concerning Transcendental Meditation that you might find interesting:

    TM is the only form of meditation currently (pending more and better research on other practices) that the American Heart Association says that doctors may recommend to their patients as an adjunctive therapy for hypertension:
    http://hyper.ahajournals.org/content/early/2013/04/22/HYP.0b013e318293645f.full.pdf+html (summary of meditation page 6)

    TM practice is credited with transforming one of the worst schools in the San Francisco Unified School District (SFUSD) into one of the best (and happiest) in that city:

    TM was taught to war refugees in Africa with extremely high PTSD symptoms and 2 studies were performed. Subjects were living in a country where they didn’t speak the language, had uncertain access to food, and were living in mud huts, on the floors of churches, or even under bushes. In the first study, PTSD symptoms from “high” to non-symptomatic after only 30 days of TM practice, while controls’ symptoms continued to worsen. This finding persisted at the 135 day followup. In the second study, similar findings were found at 30-days post-test, but 2/3 of the reduction had occurred by the 10-day post-test. International relief agencies are said to be conducting their own, independent research to confirm the findings:

    A study of very long-term practitioners of TM found that the relaxed EEG pattern found during TM practice had become a trait outside of practice, and that, as this became more clear, the meditator started to respond to the question “describe your self” differently. Once this pattern became clear enough, a pure, non-judgemental, ever-watchful, always-mindful, sense-of-self emerged and eventually became permanent, present even during deep sleep:

    Future research on TM will often include genetic and epigenetic analysis to correlate with how different subjects respond differently to the same practice:

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