By Ryan Hylton, PhD This article is based on the dissertation of Dr. Ryan Hylton who defended his thesis at PSCOM on May 16, 2022. The advantages of cryo-electron tomography In cell biology publications, many mechanistic models are built on a research team’s interpretations of relatively indirect observations. For instance, changes in protein expression levels … Continue reading The Benefits of Exploring the Unknown: How Cryo-Electron Tomography of Neuronal Growth Cones Revealed a New Function for an Old Protein

By Gaelyn Lyons On June 7th, I presented my first biomedical sciences PhD student seminar. I was excited to share the research I've done over the past year with my peers and obtain feedback that I can use moving forward. A week before my seminar, Dr. Ralph Keil, the biomedical sciences program director, sent me … Continue reading Can You Repeat That? The Importance of Rigor, Reproducibility, and Transparency in Science

By Rebecca Fleeman Over the past two decades a large portion of the public has formed unfavorable feelings towards the pharmaceutical industry1. With soaring drug prices and the opioid epidemic, many question the financial intentions of not only drug companies, but also the doctors who accept financial kickbacks from pharma. This distrust kindled government action … Continue reading Here Comes the Sun: Updates to the Sunshine Act

Comic By Madison Kuhn Based on "Human brain organoids assemble functionally integrated bilateral optic vesicles"

By Wenxue Lin, PhD This article is based on the dissertation of Dr. Wenxue Lin who defended his thesis at PSCOM on April 27, 2022. Although the prevalence of cigarette smoking has decreased from 20.9% (2005) to 14.0% (2019),1,2 cigarette smoking still remains the primary preventable cause of death in the United States and is … Continue reading Are We Winning the War on Tobacco?

Comic By Rebecca Fleeman

By Stephanie Baringer We know that science isn’t always a perfect, well, science. Despite our best efforts and rationale, things don’t always work the way we expect them too. Maybe a cytotoxic drug isn’t toxic to your cultured cells, or maybe your mouse model doesn’t behave in the anticipated way. These encounters highlight why validation … Continue reading DREADDing Validation Experiments