The War on Cancer: Targeted Therapy

Biomedical Sciences

By: Ross Keller, 3rd year PhD candidate in the Biomedical Sciences Graduate Program

Glivec_400mg (1)In an earlier post, I outlined a potential roadmap for the War on Cancer. I stated that in order to win, we need to define the genetic components of a specific cancer and design treatments based on that component. This is called targeted therapy, and it has actually already been used with success in some cancers, including certain types of leukemia, lung cancer, breast cancer, and melanoma. But what makes a good targeted therapy?

The hallmarks of a good targeted therapy are: specificity, potency, and ability to keep a cancer from relapsing. The best targeted therapies will kill cancer cells only and will do it efficiently so a resistant tumor does not occur following treatment.