What is 6 Weeks Worth? The Cost of Cancer Drugs and Extending Life

Biomedical Sciences

By: Sadie Steffens, 4th year PhD candidate in the Biomedical Sciences Graduate Program

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Source: PDPics (Pixabay)

You’d be hard-pressed to find anyone who hasn’t been affected by cancer in some way.

Second only to heart disease as the leading cause of death, many of us have friends or loved ones who have suffered from cancer. News reports with big claims about novel cancer treatments give us hope, and we have a strong desire to eradicate the disease. We want to believe that a cure is imminent, possibly even in our own lifetime.

Although we don’t discuss it much as a society, cancer affects more than our emotions. We are all paying the financial costs of cancer, costs that are escalating so quickly that they will soon be unsustainable. I’m talking about the cost of cancer drugs.

War on Cancer: Tumor Relapse

Biomedical Sciences

By: Ross Keller, 3rd year PhD candidate in the Biomedical Sciences Graduate Program

764px-Chemotherapy_vials_%281%29Chemotherapy is one of the most important aspects of cancer treatment. Although an undesirable, draining procedure, it has extended the lives many cancer patients over many decades.

However, there are significant limitations to drug therapy treatment for cancer. The biggest limitation is the fact that many tumors relapse (return) after treatment. Many don’t understand, however, why or how this happens. How does a tumor come back after it has been treated? And why do promising chemotherapy drugs usually cease to work after relapse?

The War on Cancer: Targeted Therapy

Biomedical Sciences

By: Ross Keller, 3rd year PhD candidate in the Biomedical Sciences Graduate Program

Glivec_400mg (1)In an earlier post, I outlined a potential roadmap for the War on Cancer. I stated that in order to win, we need to define the genetic components of a specific cancer and design treatments based on that component. This is called targeted therapy, and it has actually already been used with success in some cancers, including certain types of leukemia, lung cancer, breast cancer, and melanoma. But what makes a good targeted therapy?

The hallmarks of a good targeted therapy are: specificity, potency, and ability to keep a cancer from relapsing. The best targeted therapies will kill cancer cells only and will do it efficiently so a resistant tumor does not occur following treatment.